Vitro Constipation Relief is made with High Quality ingredients in a GMP Certified facility. it contains Senna Leaf Powder, Ginger Powder, Small Harad Powder, Licorice Powder, Fennel Powder, Black Pepper Powder, Black Salt, Castor Oil, and Isabgol Husk Powder we recommend 2 tablespoon of Vitro onstipation Relief powder with 1 cup of water and drinking twice daily before meals